SMALP network
SMALP Membrane Protein Conference

Register for our next Membrane Protein Conference

Our next Membrane Protein Conference is being held on March 27 from 9am-12pm MST. We'll feature nine 20 minute talks (including 5 minute Q&A) focussed on memtein structure and function, new tools and technologies for solubilization, purification and analysis in native membranes, and the latest membrane models, cell biology insights and diagnostic and therapeutic applications.

Speakers include:

Monica Gonzalez-Magaldi, Research Associate, The University of Texas at Austin will speak on the structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography, bioRxiv


Alexej Kedrov, Associate Professor, University of Düsseldorf will present on the assembly and gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa, bioRxiv


Lauren Ball, Alexander von Humboldt Postdoctoral Research Fellow, Stellenbosch University will present on An Exploration of the Universal and Switchable RAFT-Mediated Synthesis of Poly(styrene-alt-maleic acid)-b-poly(N-vinylpyrrolidone) Block Copolymers, Macromolecules


Background on SMALP

The SMALP system is being developed by the international research community as an alternative to conventional detergents, which tend to dissociate, destabilize and deactivate native membrane proteins.

SMA polymer

A variety of amphipathic polymers like styrene maleic anhydride have been found to directly and spontaneously solubilize proteins and bound lipids from membranes when activated. This provides opportunities for understanding and exploiting the structure and function of native membrane protein complexes.

As SMALP technology is relatively new, the participation of the wider community and sharing of new ideas and practices amongst researchers is the best way to ensure continued rapid development of the field.

Join our network and come to our meetings to discover how SMALP materials and methods could be used in your research.

Join our community.

The SMALP network offers polymers, methods and meetings to support the growing community of scientists and companies interested in the preparation of membrane nanodiscs formed by polymers including styrene maleic acid for biological research and drug discovery applications.

Register for a day of insightful talks from experts in the structural biology and functions of membrane proteins and nanodisc development, discussions with academic and industry leaders, and enjoy breakfast, lunch and coffee breaks on us.

These events are offered to bring together academic and industry experts, postdocs and students who are interested in membrane protein structural biology, lipidomics, proteomics, target discovery and biophysical analysis of bilayers and amphipathic polymers.

We welcome researchers from across academia and industry to join us in lively discussions and debate about the latest advances in native nanodiscs, membrane proteins, polymer chemistry, lipid biophysics, structural biology, and applications including drug discovery and delivery.